Yes, Praxis road cranksets are compatible with SRAM and Shimano drivetrains. For example, Praxis chainrings work with 10-, 11-, and 12-speed SRAM and Shimano drivetrains. This includes both mechanical and electronic shifting drivetrains. This makes Praxis cranks extremely versatile.
Please note, most Praxis road cranksets including the Zayante Carbon, Zayante Carbon-S and Alba, use a M30 spindle. These spindles use a 30 mm diameter on the drive side and 28 mm diameter on the non-drive side and require a Praxis M30 bottom bracket. Praxis offers M30 bottom brackets for most frames including BSA Threaded, PF41, 386 EVO, BB30, PF30, T47 and more.